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Phentermine in Brief

Phentermine was approved by the FDA in 1959. It is remarkable that a drug has managed to maintain market dominance for fifty years. Few drugs have managed to survive that long. As medical science has progressed, new discoveries have produced better treatments in most areas. This was one of the first appetite suppressants and, despite the best efforts of research scientists around the world, it is still probably the best way to keep a diet going. Phentermine helps people lose weight when combined with a sensible diet, some gentle physical exercise and general lifestyle changes.

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What does the medical research actually prove?

There is clear evidence from decades of research into weight loss that, when the results of phentermine are compared against the placebo groups, phentermine always significantly outperforms the placebo. But, and this represents the key issue, the amount of weight lost rapidly declines over time. That means, even when people have the support of phentermine, it is really hard to keep to a diet. With the support of an appetite suppressant, people do keep their motivation to diet for longer and so have the best chance of losing weight. In other words, the science of weight loss is not directly related to any drug. People have to have the commitment to change their lifestyles.

What do the doctors have to say?

There are no long term clinical trials using phentermine. In all the fifty years of sale, research has focussed on short-term use. So people put on weight over years and then scientists study how a few weeks with a drug affects them. This is not a very sensible strategy. Doctors therefore have to rely on their patients to tell them how good phentermine is. The experience on the ground shows patients have always come back for more. If there were bad experiences and weight stayed put, phentermine would have died on the vine years ago. Poor performers do not survive in this global market where the internet brings bad news faster than a speeding bullet.